So before anybody get's upset and says that this is extreme I'm simply relaying some information about a treatment that proved to be 100% effective after years of failed alternatives.
My ex had experienced years of skin problems that had started to leave permanent marks especially around the jaw line and this was starting to present emotional/psychological implications.
She went to see a private clinic on Harley Street and was, after two consultations and a number of precautionary tests to check that the potential for side effects was limited to within reasonable / acceptable probability a course of a drug called Roaccutane.
I've posted a link to the NHS site below as there is a fair bit of web content on this - some useful, some rather un helpful and the usual 'shouty', ill informed stuff - noting that ALL drugs have side effects.
https://beta.nhs.uk/medicines/isotretinoin-capsules/
This worked for my ex with non of the side effects other than the physical, short term ones that are 100% expected. It wasn't cheap but it did fix the problem. Her confidence improved and she didn't spend her time worrying about when the next outbreak of acne like inflammation was coming.
Hope this is helpful and best of luck